How to do a Mecke Drug Test

This entry is part 5 of 9 in the series Psychoactive Self-sufficiency

Mecke reagent is commonly used as a simple spot-test to presumptively identify amphetamines, DXM, cathinones (“bath salts”), opiates, and 2C’s. A drop or two of Mecke (which turns dark in colour over time, although will still work as long as reaction colours can still be distinguished) is added to a small amount of the test substance, and the resulting colour change and its duration compared to a reference chart of known colour reactions. Different compounds produce different colour reactions.

Performing a Mecke Drug Test

Mecke reagent is a mix of sulphuric acid and selenious acid, and therefore highly toxic, and strongly corrosive. Mecke can be absorbed through the skin, and should only be stored in glass or porcelain containers.

  1. Put a drop of reagent on a glass or porcelain surface.
  2. Take a small sample of the substance and add it to the reagent.
  3. Immediately compare the resulting colour change to the references below. No colour change after one minute should be taken as a sign of the presence of one or more unknown substances.
Click to enlarge

Click to enlarge

Mecke Reagent Colour Results


Chlorpromazine HCl
Diacetylmorphine HCl (Heroin)
Dimethoxy-meth HCl
Doxepin HCl
Mescaline HCl
Morphine monohydrate
Oxycodone HCl
Propoxyphene HCl


Blackish red
Very dark bluish green
Deep bluish green
Dark brown
Very dark red
Light olive brown
Dark greyish yellow
Greenish black
Dark greyish olive
Very dark bluish green
Moderate olive
Very dark bluish green
Olive black
Moderate olive
Deep reddish brown
Brilliant greenish yellow

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